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We would like to inform you that Viatris, the marketing authorisation holder for Creon® has decided to increase the capsule length of Creon® 25000 from 21.7mm to 24.2mm. The diameter of the capsule will not change.

The new size of Creon® 25000 capsule does not affect the efficacy of the product and should not have an impact on the patient’s ability to swallow the capsules whole.

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Writing a Creon® prescription

Pancreatic Enzyme Replacement Therapies (PERTs) are biological formulations. Different products are not interchangeable as they contain different proportions of lipase, protease and amylase.1-7

When writing a prescription for Creon®, be sure to specify the strength and quantity, as abbreviations may be misinterpreted.8

References

  1. Creon® Micro Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/5564/smpc. Last accessed: December 2023
  2. Creon® 10000 Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1167/smpc. Last accessed: December 2023
  3. Creon® 25000 Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1168/smpc. Last accessed: December 2023
  4. Nutrizym 22 Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/11883. Last accessed: December 2023
  5. Pancrease HL Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1511. Last accessed: December 2023
  6. Pancrex V Capsules Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1054/smpc. Last accessed: December 2023
  7. Pancrex V Powder Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/1056/smpc. Last accessed: December 2023
  8. General Prescribing Guidance. Available at: https://patient.info/doctor/general-prescribing-guidance. Last accessed: December 2023
  9. Imrie CW, et al. Review article: enzyme supplementation in cystic fibrosis, chronic pancreatitis, pancreatic and periampullary cancer. Aliment Pharmacol Ther. 2010; 1:1-25.
  10. Munck A. Nutritional considerations in patients with cystic fibrosis. Expert Rev Resp Med. 2010; 4(1) 47-56.

Creon® is designed to deliver effective dosing to all patients using the fewest number of capsules.

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Please continue to report suspected adverse drug reactions and device failures with any medicine or vaccine to the MHRA through the Yellow Card Scheme. It is easiest and quickest to report adverse drug reactions and device failures online via the Yellow Card website: https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or Apple App Store. Alternatively, you can report via some clinical IT systems (EMIS/SystmOne/Vision/MiDatabank) or by calling the Commission on Human Medicines (CHM) free phone line: 0800-731-6789.
Adverse reactions/events and device failures should also be reported to MAH at e-mail address: pv.uk@viatris.com.

This website is intended for UK healthcare professionals. If you are a patient who has been prescribed Creon® please click here

Viatris UK Healthcare Limited (company registration number 09189103), an English company with a registered office address at 20 Station Close, Potters Bar, Hertfordshire, EN6 1TL (VAT - 421 623 781).

Creon® is indicated for the treatment of pancreatic exocrine insufficiency.

CRE-2021-0769 December 2023.

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