Mylan has decided to voluntarily discontinue Creon 40K from June 2019. This decision is not associated with any safety or efficacy findings. Compared to all other doses, producing Creon 40K requires a different concentration of active enzymes which have been decreasing over the last few years and because of this Creon 40K has experienced frequent supply constraints.
It is important to note that, Creon Micro, Creon 10K and Creon 25K will continue to be manufactured.
Creon capsules are interchangeable, and patients can achieve the higher dose by taking more of the lower strength capsules. Patients should not be concerned about the efficacy when switching to a lower strength capsule.
Information for Patients and Prescribers
Mylan is unable to make any specific treatment recommendations to healthcare professionals or for individual patients, however, it is recommended that patients speak to their treating physician to discuss treatment options according to their health needs and their relevant clinical history.
About Creon
Creon is a Pancreatic Enzyme Replacement Therapy (PERT) that helps patients with Pancreatic Exocrine Insufficiency (PEI) to break down food and digest nutrients by replacing the pancreatic enzymes made by a healthy pancreas. The active substance of Creon is pancreatin, a natural substance from the pancreas of the pig; as a biologic product Creon is produced using a complex manufacturing process that is subject to high standards and strict requirements in terms of quality and compliance.
Contact Information
If you require additional information or have any questions, please contact +44(0) 1707 853 100.
CRE-2019-0180
DOP: April 2019
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