Dosing & administration in children
Creon® 10,000 and Creon® Micro (5,000 lipase units per 100 mg scoop) allow you to prescribe a smaller dose to babies and younger children.
DOSING WITH CREON MICRO
- Initially 100 mg of Creon® Micro (one measure equal to 5,000 lipase units) should be taken with each feed or meal1
- Dose increases, if required, should be added slowly with careful monitoring of response and symptoms1
- Titrate dose upwards as necessary to control symptoms and achieve adequate weight gain2
- Doses should not exceed 10,000 units of lipase/kg/day1
Administration of Creon® Micro
- In young infants: Creon® Micro granules should be mixed with a small amount of apple juice and given from a spoon directly before the feed.
- In weaned infants: granules should be taken with acidic liquids or soft foods (e.g. mixed with apple juice or apple puree), but without chewing, directly before the meal.
- The apple juice should not be diluted.
- Granules can be mixed with a small amount of milk and administered to the infant immediately.
- The granules should not be added to the baby's bottle.
- Once mixed, give directly from a spoon ensuring that the infant swallows all the granules immediately and none are left on their infant’s face, around their mouth, or in their gums.1
Dosing with Creon® 10,000
- Initially one or two capsules with each meal.
- Dose increases, if required, should be added slowly, with careful monitoring of response and symptomatology.
Administration of Creon® capsules
- Encourage young children to swallow the capsules whole as early as they can, or
- Open the capsule and mix the granules with acidic liquids or soft food1,3
- Care should be taken to ensure that no product is retained in the mouth.
As children grow they are likely to increase their Creon® dose and take more capsules per meal. To help improve compliance and efficacy and to minimise pill burden, consider moving children to Creon® 25,000 capsules.
- Creon® Micro Summary of Product Characteristics. 2019.
- Munck A et al. Expert Rev Resp Med. 2010; 4(1): 47-56.
- Creon® Micro Patient Information Leaflet. 2015.